逆轉(zhuǎn)錄病毒 iPSC 重編程試劑盒

Induced pluripotent stem cells (also known as iPS cells or iPSCs) hold great promise in the field of regenerative medicine. Because they are not only similar to endogenous pluripotent stem cells with the capability of self-renewal and differentiation but also able to be generated from multiple cell types in the body (such as fibroblast and blood cells). Therefore, iPSCs are an invaluable resource for drug discovery, cell therapy, and basic research.

Since the pioneer method developed by Dr. Yamanaka in 2006, several methods have been developed to generate integration-free iPSCs, including adenovirus, Sendai virus, the piggyBac system, minicircle vector, episomal vectors, direct protein delivery and synthesized mRNA. However, the somatic cell reprogramming to iPSC is a comprehensive and reagents-sensitive process. Without the optimized reagents and method, the efficiency in generating iPSC is quite low.

We provide two easy-to-use and highly efficient iPSC reprogramming kits, episomal iPSC reprogramming kit and retrovirus iPSC reprogramming kit. With these fully optimized reprogramming kits, you will generate desired iPSC from different somatic cell types with high success rate.

Description:Human induced pluripotent stem cells (iPSCs) can be derived from somatic cells through a reprogramming process driven by ectopic expression of a defined set of reprogramming factors: Oct4, Sox2, Klf4 and c-Myc. These hiPSCs share the properties of self-renewal and pluripotency with human ES cells, and can therefore be used as a renewable source for all differentiated cell types of the body. Human iPSCs can be generated from patients of virtually any genetic background. Retroviruses are efficient tools for delivering heritable genes into the genome of dividing cells. The VSV-G pseudotyped retrovirus has a wide range of targets including both mammalian and non-mammalian cells, and are usually silenced in ES cells. The retrovirus is commonly used in generating iPSCs because of its high reprogramming efficiency. The Human iPS Cell Reprogramming Retrovirus Kit offers such opportunity to generate iPSCs from various tissues and cell types.

Product Name：Retrovirus iPSC Reprogramming Kit
Shipping Condition：Dry Ice - Overnight Shipping
Storage and Stability：Store at -80 °C. This product is stable up to 6 months when stored as directed.
Quality Control：Each lot of Human iPS Cell Reprogramming Retrovirus Kit is tested for sterility and successful reprogramming.
Restricted Use：For Research Use Only. Not for use in diagnostic or therapeutic procedures.

逆轉(zhuǎn)錄病毒 iPSC 重編程試劑盒