Anti-α-ACTN4抗體,α-輔肌動(dòng)蛋白4抗體產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-1741R

英文名稱 alpha Actinin 4-Loading Control
中文名稱 α-輔肌動(dòng)蛋白4(內(nèi)參)抗體
別    名 Actinin alpha 4; alpha-Actinin 4; alpha Actinin-4; actinin 4; actinin4; actinin-4; ACTN 4; ACTN4; DKFZp686K23158; F actin cross linking protein; FSGS 1; FSGS; FSGS1; Non muscle alpha actinin 4.
產(chǎn)品類型 內(nèi)參抗體 
研究領(lǐng)域 免疫學(xué)  發(fā)育生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  結(jié)合蛋白  細(xì)胞骨架  
分 子 量 105kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-α-ACTN4抗體,α-輔肌動(dòng)蛋白4抗體產(chǎn)品介紹 

      F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Subunit:
Homodimer; antiparallel. Binds TRIM3 at the N-terminus. Identified in a complex with CASK, IQGAP1, MAGI2, NPHS1, SPTAN1 and SPTBN1. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with BAIAP1 and PDLIM2.

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