Mouse   Anti-Metronidazole抗體售后服務(wù)

FROM: ABCAM

Catalog Number : BYK-2059R       
Quantity size :   200ug  (0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide)

Anti-Metronidazole抗體售后服務(wù)Background: Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria.

Specificity :   

• Anti- Metronidazole is a mouse monoclonal antibody unconjugated                
• specific for Metronidazole of Metronidazole,          
• use for western blotting,elisa,immunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification, purity :>95%
• Isotype:  IgG

Anti-Metronidazole抗體售后服務(wù)Application :  

• ELISA 1:500-1000
• IF=1:100-500                  
• Optimal working dilutions must be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Anti-Metronidazole抗體售后服務(wù)Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.