背景介紹：MAGE-H1 is a 219 amino acid protein that contains a type II MAGE homology domain (MHD). Enhanced ligand stimulation promotes MAGE-H1 interaction with the type II death domain of NGFR p75. It is suggested that MAGE-H1 accelerates differentiation in response to nerve growth factor in cells.

Function:
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.

別名：dJ730K3.2; MAGI-3; magi3; MAGI3_HUMAN; Membrane Associated Guanylate kinase Related 3; Membrane-associated guanylate kinase; Membrane-associated guanylate kinase inverted 3; RP4-730K3.1; SLIPR; WW and PDZ domain-containing protein 3.  

膜相關鳥苷酸激酶3抗體,Anti-MAGI3抗體簡單介紹：

產(chǎn)品編號：BYK-18629R

英文名稱：Anti-MAGI3
中文名稱：膜相關鳥苷酸激酶3抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應、產(chǎn)品應用 （具體交叉反應與產(chǎn)品應用請或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

膜相關鳥苷酸激酶3抗體,Anti-MAGI3抗體產(chǎn)品信息：

免疫組化問題解答

染色弱？

原因：抗體濃度過低、孵育時間過短

解決方法：提高抗體濃度、孵育時間不能少于60分鐘  

原因：試劑超過有效使用時間 

解決方法：應更換試劑 

原因：操作中添加試劑時緩沖液未瀝干 

解決方法：每步滴加試劑前瀝干切片中多余的緩沖液 使試劑稀釋 （應防止切片干燥） 

原因：室溫太低，低于15度 

解決方法：要改放在37度孵育箱孵育30-60分鐘或4度冰箱過夜 

原因：蛋白封閉過度 

解決方法：封閉不要超過12分鐘

染色陰性？

原因：操作步驟錯誤

解決方法：應重試，設陽性對照

原因：組織中無抗原

解決方法：設陽性對照以驗證試驗結果

原因：一抗與二抗種屬連接錯誤

解決方法：仔細確定一抗二抗種屬無誤

膜相關鳥苷酸激酶3抗體,Anti-MAGI3抗體相關產(chǎn)品：

Anti-RAR alpha 維甲酸受體RAR α/RAR α抗體
Anti-LC3A/B 自噬微管相關蛋白輕鏈3A/3B抗體
Anti-phospho-c-Raf(Ser338/Tyr340) 磷酸化原癌基因c-Raf抗體
Anti-RAP1A 抗Rap1A抗體
Anti-ATRNL1 ATRNL1蛋白抗體
Anti-RAD51C抗體
Anti-Kv2.2 電壓門控性鉀通道Kv2.2抗體
Anti-Rad52 Rad52抗體
Anti-LRRTM4 富含*重復跨膜神經(jīng)元蛋白4抗體
Anti-SH3TC2 脫髓鞘相關蛋白SH3TC2N抗體
Anti-Rad51 Rad51抗體
Anti-Securin/PTTG 垂體腫瘤轉化基因抗體
Anti-SCDO3/Lunatic Fringe 信號轉導分子SCDO3抗體
Anti-Parvalbumin  細小清蛋白抗體
Anti-NAB2/MADER EGR1結合蛋白2抗體