背景介紹：PROSC is a 275 amino acid ubiquitously expressed enzyme that is highly conserved from bacteria to mammals. The gene encoding PROSC is cotranscribed with proline sythetase. PROSC requires the cofactor pyridoxal phosphate, the active form of vitamin B6 that acts in all transamination reactions. The PROSC gene maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

別名：FLJ11861; Proline synthase co-transcribed bacterial homolog protein; Proline synthetase co transcribed bacterial homolog; Proline synthetase co transcribed homolog (bacterial); PROSC; PROSC_HUMAN.  

PROSC蛋白抗體，Anti-PROSC抗體簡(jiǎn)單介紹：

產(chǎn)品編號(hào)：BYK-19184R

英文名稱：Anti-PROSC
中文名稱：PROSC蛋白抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請(qǐng)或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

PROSC蛋白抗體，Anti-PROSC抗體產(chǎn)品信息：

博研生物小課堂：

常用激光器對(duì)應(yīng)熒光素的選擇：

藍(lán)色激光器熒光素（488nm）：Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7

紅色激光器熒光素（633nm）：APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647

黃色激光器熒光素（561nm）：PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594

1.陽性細(xì)胞染色分布有三種類型：細(xì)胞漿、細(xì)胞核、細(xì)胞膜表面。大部分抗原見于細(xì)胞漿，可見于整個(gè)胞漿或部分胞漿

2.陽性細(xì)胞分布可分為灶型和彌漫性

3.由于細(xì)胞內(nèi)含抗原量不同，所以染色強(qiáng)度不一。如果細(xì)胞之間染色強(qiáng)度相同，常提示其反應(yīng)為非特異性

4.陽性細(xì)胞染色定位于單個(gè)細(xì)胞，且與陰性細(xì)胞相互交雜分布；而非特異性染色常不限于單個(gè)細(xì)胞，而是累及一片細(xì)胞。

5.切片邊緣、刀痕或褶皺區(qū)域，壞死或擠壓的細(xì)胞區(qū)，膠原結(jié)締組織等，常表現(xiàn)為相同的陽性染色強(qiáng)度，不能用于判斷陽性。

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