背景介紹：This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into plaet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. 

別名：Calcium dependent phospholipid binding protein; CPLA 2; cPLA2 alpha; cPLA2; Cytosolic phospholipase A2; Cytosolic phospholipase A2 group IVA; Lysophospholipase; MGC126350; PA24A_HUMAN; Phosphatidylcholine 2 acylhydrolase; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2 group 4 A; Phospholipase A2 group IVA (cytosolic calcium dependent); Phospholipase A2 group IVA; PhospholipaseA2; PLA2G4.    

胞漿型磷脂酶A2抗體，Anti-CPLA2抗體簡單介紹：

產(chǎn)品編號：BYK-20212R

英文名稱：Anti-CPLA2
中文名稱：胞漿型磷脂酶A2抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

胞漿型磷脂酶A2抗體，Anti-CPLA2抗體產(chǎn)品信息：

博研生物小課堂：

常用激光器對應(yīng)熒光素的選擇：

藍(lán)色激光器熒光素（488nm）：Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7

紅色激光器熒光素（633nm）：APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647

黃色激光器熒光素（561nm）：PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594

1.陽性細(xì)胞染色分布有三種類型：細(xì)胞漿、細(xì)胞核、細(xì)胞膜表面。大部分抗原見于細(xì)胞漿，可見于整個胞漿或部分胞漿

2.陽性細(xì)胞分布可分為灶型和彌漫性

3.由于細(xì)胞內(nèi)含抗原量不同，所以染色強(qiáng)度不一。如果細(xì)胞之間染色強(qiáng)度相同，常提示其反應(yīng)為非特異性

4.陽性細(xì)胞染色定位于單個細(xì)胞，且與陰性細(xì)胞相互交雜分布；而非特異性染色常不限于單個細(xì)胞，而是累及一片細(xì)胞。

5.切片邊緣、刀痕或褶皺區(qū)域，壞死或擠壓的細(xì)胞區(qū)，膠原結(jié)締組織等，常表現(xiàn)為相同的陽性染色強(qiáng)度，不能用于判斷陽性。

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