背景介紹：The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

別名：CDC42 binding protein kinase alpha; CDC42 binding protein kinase alpha (DMPK like); CDC42 binding protein kinase alpha; CDC42 binding protein kinase alpha dmpk like; CDC42 binding protein kinase beta; CDC42-binding protein kinase alpha; CDC42BPA; DKFZp686L1738; DMPK like; DMPK-like alpha; FLJ23347; KIAA0451; MRCK alpha; mrck; mrcka; MRCKA_HUMAN; Myotonic dystrophy kinase related CDC42 binding protein kinase alpha; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; Myotonic dystrophy protein kinase-like alpha; OTTHUMP00000035727; OTTHUMP00000035728; OTTHUMP00000035729; OTTHUMP00000035730; pk428; RP5-1087E8.4; Ser thr protein kinase PK428; Ser thr protein kinase related to the myotonic dystrophy protein kinase; Serine/threonine protein kinase MRCK alpha; Serine/threonine-protein kinase MRCK alpha; DKFZp686P1738; MGC189823; A930014J19Rik.  

CDC42結(jié)合蛋白激酶α抗體,Anti-MRCKα抗體簡單介紹：

產(chǎn)品編號：BYK-10952R

英文名稱：Anti-MRCK alpha
中文名稱：CDC42結(jié)合蛋白激酶α抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

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性    狀 Lyophilized or Liquid
濃    度 1mg/ml

CDC42結(jié)合蛋白激酶α抗體,Anti-MRCKα抗體產(chǎn)品信息：

博研生物小課堂：

常用激光器對應(yīng)熒光素的選擇：

藍(lán)色激光器熒光素（488nm）：Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7

紅色激光器熒光素（633nm）：APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647

黃色激光器熒光素（561nm）：PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594

構(gòu)象決定簇(conformational determinants),又稱為不連續(xù)決定簇(discontinuous determinants),抗原分子中由分子基團(tuán)間特定的空間構(gòu)象決定的決定簇,一般是由分子中不連續(xù)的若干肽鏈盤繞折疊而構(gòu)成。

順序決定簇(sequential determinants),又稱為連續(xù)決定簇(continuous determinants),抗原分子中直接由分子基團(tuán)的一級結(jié)構(gòu)序列決定的決定簇。

一般來講,二種決定簇都依賴于多肽鏈上的某一段氨基酸序列,空間構(gòu)象也是由一級序列決定的。因此決定簇都依賴于空間構(gòu)象和氨基酸序列兩種因素。

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