“載脂蛋白A1抗體,Anti-FAS/Apo-1/CD95抗體”應用于IHC、WB、 IF、IP、ELISA，質(zhì)量保證，無效免費退換，另外本公司生產(chǎn)經(jīng)營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！

產(chǎn)品介紹：

【產(chǎn)品名稱】：載脂蛋白A1抗體,Anti-FAS/Apo-1/CD95抗體

【產(chǎn)品類型】：一抗

【產(chǎn)品編號】：BYk-0215R                    

【相關標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 狀】： Lyophilized or Liquid

【濃 度】： 1mg/1ml

【亞 型】： IgG

【規(guī) 格】：0.1ml/100ug，0.2ml/200ug

【抗體來源】： Rabbit OR MOUSE

【克隆類型】： polyclonal or monoclonal

【產(chǎn)品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應的標記抗體有HRP標記抗體，F(xiàn)ITC標記，BIO等。

【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【信息詳情】： FAS is a receptor for TNFSF6/FASL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex （DISC） performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases （aspartate-specific cysteine proteases） mediating apoptosis. Apoptosis or programmed-cell death is a physiological process essential for the normal development and maintenance of homeostasis in many organisms. This “cellular suicide” can be mediated by the Fas antigen （CD95, APO1）, a cell-surface glycoprotein, 40-50kDa, that belongs to the nerve growth factor/tumor necrosis factor （TNF） receptor family. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both （By similarity）. It is type I membrane protein. Contains a death domain involved in the binding of FADD, and maybe to other cytosolic adaptor proteins Contains 1 death domain.

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