Anti-SPIRE2抗體,SPIRE2蛋白抗體說明產(chǎn)品介紹：Spir-2 is a 714 amino acid protein belonging to the spire family. Spir-2 is a cytoplasmic protein that contains one KIND domain and three WH2 domains. Spir-2 binds to actin via the WH2 domains and acts as an actin nucleation factor. Spir-2 is involved in vesicle transport and acts as a link between actin organization and intracellular transport. Spir-2 is expressed as four isoforms that are produced by alternative splicing events. The gene that encodes Spir-2 maps to human chromosome 16, which encodes over 900 genes and approximay 90 million base pairs, making up nearly 3% of human cellular DNA. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲，保質(zhì)期六個月，*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復(fù)凍融，保質(zhì)期一年。

產(chǎn)品名稱 Anti-SPIRE2抗體,SPIRE2蛋白抗體說明

產(chǎn)品編號 BYK-17678R

英文名稱 SPIRE2
中文名稱 SPIRE2蛋白抗體
別    名 MGC117166; Protein spire homolog 2; Spir-2; SPIR2_HUMAN; Spire homolog 2 (Drosophila); SPIRE2.
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架          

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請）

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