Rabbit Anti-VEGFR2 antibody直銷

Catalog Number : BYK-10412R-Bio      

Quantity size :   100ug (2mg/1ml, Lyophilized or Liquid. Buffer = Preservative:15Mm Sodium Azide, Constituents: 0.1% BSA ,0.01M PBS, pH 7.4.Or Lyophilized or Liquid, glycerol free. Reconstitute with 50ul sterile distilled water.)

Background:  Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Also known as: VEGF Receptor 2; CD309; CD309 antigen; Fetal liver kinase 1; FLK-1; FLK1; KDR; Kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; Tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR 2; VEGFR; VEGFR-2; VEGFR2; VGFR2_HUMAN.

Specificity:   -Rabbit Polyclonal IgG, affinity purified by Protein A.

- Biotin conjugated

-Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep 

-Immunogen: KLH conjugated synthetic peptide derived from human VEGFR2.

-Predicted molecular weight: 147kDa

Application:  WB=1:50-200     ELISA=1:100-1000 

IHC-P=1:50-200   IHC-F=1:50-200 

ICC=1:50-200     IF=1:50-200

            Not yet tested in other applications.

            Optimal working dilutions must be determined by the end user.

Storage:     Store at -20 °C for one year. Avoid repeated freeze/thaw

            cycles. The Lyophilized or Liquid antibody is stable at room

            temperature for at least one month and for greater than a year when

            kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or

            diluent of antibody the antibody is stable for at least two weeks at

            2-4 °C.

Important Note: This product as supplied is intended for research

             use only, not for use in human, therapeutic or diagnostic

             applications..