Anti-CD16/PE抗體代測(cè)kit

Catalog Number : BYK-6028R-PE      
Quantity size :   100ug (2mg/1ml, Lyophilized or Liquid. Buffer = 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide. Reconstitute with 50ul sterile distilled water.)

Background:  This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer(NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Also known as: FCG3A_HUMAN; FCGR3_HUMAN; CD 16; CD 16a; CD16A; CD16a antigen; CD16B; CD16b antigen; Fc fragment of IgG; Fc fragment of IgG low affinity IIIa receptor (CD16); Fc fragment of IgG, low affinity III, receptor (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc fragment of IgG, low affinity IIIb, receptor for (CD16); Fc gamma R3; Fc gamma receptor IIIA; Fc gamma receptor IIIb (CD 16); Fc gamma RIII alpha; Fc gamma RIII; Fc gamma RIII beta; Fc gamma RIIIa; Fc gamma RIIIb; Fc of IgG; Fc-gamma receptor III2 (CD 16); Fc-gamma receptor III2 (CD16); Fc-gamma receptor IIIb (CD16); FCG 3; FCG3; FCgammaRIIIA; FCGR 3; FCGR 3A; FCGR3; FCGR3A; FCGR3A protein; FCGRIII; FcR 10; FcR10; FcRIII; FcRIIIa; IGFR 3; IGFR3; IgG Fc receptor III 1; IgG Fc receptor III 2; immunoglobulin G Fc receptor III; Low affinity IIIa receptor; Low affinity immunoglobulin gamma Fc region receptor III A; Low affinity immunoglobulin gamma Fc region receptor IIIB; neutrophil-specific antigen NA.

 Specificity:   -Rabbit Polyclonal IgG, affinity purified by Protein A.

-PE conjugated

-Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep

-Immunogen: KLH conjugated synthetic peptide derived from hu CD133.

-Predicted molecular weight: 27kDa

Application:  Flow-Cyt=1:50-200 IF=1:50-200

            Excitation spectrum: 520-570nm

            Emission spectrum: 490-510nm

            Not yet tested in other applications.

            Optimal working dilutions must be determined by the end user.

Storage:     Store at -20 °C for one year. Avoid repeated freeze/thaw

            cycles. The Lyophilized or Liquid antibody is stable at room

            temperature for at least one month and for greater than a year when

            kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or

            diluent of antibody the antibody is stable for at least two weeks at

            2-4 °C.

 Important Note: This product as supplied is intended for research

             use only, not for use in human, therapeutic or diagnostic

             applications..