Anti-CD163/FITC抗體

Catalog Number : BYK-2527R-FITC      
Quantity size :   100ug (2mg/1ml, Lyophilized or Liquid. Buffer = 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide. Reconstitute with 50ul sterile distilled water.)

Anti-CD163/FITC抗體Background:  CD163 is a 130 kDa membrane glycoprotein. It is a member of the scavenger receptor cysteine-rich superfamily and is a receptor for the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone. Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant.

Also known as: Scavenger receptor cysteine-rich type 1 protein M130; CD 163; CD163 antigen; CD163 molecule; Hemoglobin Scavenger Receptor; M130; M130 antigen precursor; Macrophage associated antigen; MM130; C163A_HUMAN.

Specificity:   -Rabbit Polyclonal IgG, affinity purified by Protein A.

-FITC conjugated

-Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse

-Immunogen: KLH conjugated synthetic peptide derived from human CD163.

-Predicted molecular weight: 130kDa

Anti-CD163/FITC抗體Application:    Flow-Cyt=1:50-200 IF=1:50-200

              Excitation spectrum: 490-495nm

              Emission spectrum: 520-530nm

              Not yet tested in other applications.

              Optimal working dilutions must be determined by the end user.

Storage:      Store at -20 °C for one year. Avoid repeated freeze/thaw

             cycles. The Lyophilized or Liquid antibody is stable at room

             temperature for at least one month and for greater than a year when

             kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or

             diluent of antibody the antibody is stable for at least two weeks at

             2-4 °C.

Anti-CD163/FITC抗體Important Note: This product as supplied is intended for research

              use only, not for use in human, therapeutic or diagnostic

              applications..