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Anti-TNFRSF18/GITR抗體,糖皮質激素誘導腫瘤壞死因子受體抗體供應商

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產品名稱:Anti-TNFRSF18/GITR抗體,糖皮質激素誘導腫瘤壞死因子受體抗體供應商
中文名稱:糖皮質激素誘導腫瘤壞死因子受體抗體
英文名稱:Anti-TNFRSF18/GITR
產品編號:BYK-1173R
產品別名:Activation inducible TNFR family receptor; Activation-inducible TNFR family receptor; CD357; AITR; GITR; GITR D; GITR-D; GITRD; Glucocorticoid induced TNFR related protein; glucocorticoid-induced tnf receptor ligand; Glucocorticoid induced TNFR related protein; TNF receptor superfamily activation inducible protein; Glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation inducible protein; TNR18_HUMAN; TNFRSF 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; Tumor necrosis factor receptor superfamily member 18 precursor.

本公司另供應“糖皮質激素誘導腫瘤壞死因子受體抗體”的標記有:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC.
產品規(guī)格:100ug/200ug
產品濃度: 1mg/1ml
抗體來源:兔源、鼠源、山羊
克 ?。簡慰寺】贵w、多克隆抗體
抗體類型:一抗
性 狀: 凍干粉或液體
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-TNFRSF18/GITR抗體,糖皮質激素誘導腫瘤壞死因子受體抗體供應商技術說明,產品*,由于篇幅原因,更多信息請:

Rabbit Anti-human IgG Whole serum  兔抗人IgG抗血清
Rabbit Anti-human IgM Whole serum  兔抗人IgM抗血清
Rabbit Anti-human IgA Whole serum  兔抗人IgA抗血清
Rabbit Anti-human IgGF(ab')2 Whole serum  兔抗人IgGF(ab')2抗血清
Rabbit Anti-mouse IgG-Fc Whole serum  兔抗小鼠IgG-Fc抗血清
Rabbit Anti-human k-chain Whole serum  兔抗人k-鏈抗血清
Rabbit Anti-human γ-chain Whole serum  兔抗人γ-鏈抗血清
Rabbit Anti-chicken IgM Whole serum  兔抗雞IgM抗血清
Rabbit Anti-digoxin Whole serum  兔抗地高辛抗血清
Rabbit Anti-dog IgG Whole serum  兔抗狗IgG抗血清
Rabbit Anti-FITC Whole serum  兔抗熒光素抗血清
Rabbit Anti-Goat IgG Whole serum  兔抗羊IgG抗血清
Rabbit Anti-Goat IgM Whole serum  兔抗羊IgM抗血清
Rabbit Anti-Guinea IgG Whole serum  兔抗豚鼠IgG抗血清
Rabbit Anti-Guinea IgM Whole serum  兔抗豚鼠IgM抗血清
Rabbit Anti-horse IgG Whole serum  兔抗馬IgG抗血清
Rabbit Anti-HRP Whole serum  兔抗HRP抗血清

產品介紹:
TNFRSF18 or GITR (glucocorticoid-induced TNF receptor family-regulated gene) is a 25 kD TNF receptor superfamily member (also known as AITR and TNFRSF18) originally identified in the mouse by comparing untreated and dexamethasone-treated murine T cell hybridoma cells. Human GITR was subsequently identified by searching an expressed sequence tag database. GITR is expressed on activated lymphocytes and is upregulated by T cell receptor engagement. The cytoplasmic domain of GITR is homologous to CD40, 4-1BB and CD27 and has been shown to interact with TRAF 1-3, but not TRAF 5 or 6. GITR signaling has been shown to regulate T cell proliferation and TCR-mediated apoptosis, and to break immunological self-tolerance. GITR appears to be highly expressed on CD4+CD25+ T regulatory cells and has been shown to induce NF-kB activation through TRAF2/NIK signaling. GITR has been proposed to be involved in the development of regulatory T cells and to regulate the activity of Th1 subsets. GITR binds GITRL, a TNF superfamily ligand expressed on endothelial cells, dendritic cells, macrophages, and B cells.

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