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當(dāng)前位置:上海博研生物工程研究中心>>科研抗體>>一抗>> Anti-SLC6A4抗體,5-羥色胺轉(zhuǎn)運(yùn)蛋白抗體說明

Anti-SLC6A4抗體,5-羥色胺轉(zhuǎn)運(yùn)蛋白抗體說明

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     Anti-SLC6A4抗體,5-羥色胺轉(zhuǎn)運(yùn)蛋白抗體說明產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-1893R

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G

英文名稱 SLC6A4
中文名稱 5-羥色胺轉(zhuǎn)運(yùn)蛋白抗體
別    名 Serotonin transporter; 5HT transporter; 5-HTT; 5-HTTLPR; 5HTT; hSERT; HTT; OCD1; SERT; SERT1; SC6A4_HUMAN; SERT; SLC6A4; Sodium dependent serotonin transporter; Sodium-dependent serotonin transporter; Solute carrier family 6 member 4; sodium-dependent serotonin transporter; 5-hydroxytryptamine transporter; 5HT transporter; Na+/Cl- dependent serotonin transporter. 
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  細(xì)胞膜受體  藥物及化合物  轉(zhuǎn)運(yùn)蛋白  新陳代謝  
分 子 量 70kDa
細(xì)胞定位 細(xì)胞膜 

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù),具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)!

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-SLC6A4抗體,5-羥色胺轉(zhuǎn)運(yùn)蛋白抗體說明產(chǎn)品介紹 


      This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. 

Function:
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.


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