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Anti-Adenosine Receptor A2a抗體,腺苷A2A受體抗體產(chǎn)品詳細資料
產(chǎn)品編號 BYK-1456R
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
亞 型 IgG
純化方法 affinity purified by Protein G
英文名稱 Adenosine Receptor A2a
中文名稱 腺苷A2A受體抗體
別 名 Adenosine Receptor A2a; Adenosine A2A-R; A2AR; A2A adenosine receptor; A2AAR; A2aR; ADENO; Adenosine A2 receptor; Adenosine A2a receptor; Adenosine receptor subtype A2a; Adenosine Receptor A2a; ADORA 2; ADORA2; Adora2a; hA2aR; RDC 8; RDC8; AA2AR_HUMAN.
研究領(lǐng)域 心血管 細胞生物 信號轉(zhuǎn)導 細胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子
分 子 量 45kDa
細胞定位 細胞膜
抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應用不做依據(jù),具體產(chǎn)品應用與實驗稀釋比請!
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Anti-Adenosine Receptor A2a抗體,腺苷A2A受體抗體產(chǎn)品介紹
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
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