Anti-AARS2抗體,丙氨酰tRNA合成酶2抗體產(chǎn)品詳細資料

產(chǎn)品編號 BYK-1512R

英文名稱 AARS2
中文名稱 丙氨酰tRNA合成酶2抗體
別    名 alanyl tRNA synthetase 2; AARSL; bA444E17.1; Gm89; MT ALARS; MTALARS ; AARS 2; AARS2; Alanine tRNA ligase 2 mitochondrial; Alanine tRNA ligase; Alanyl tRNA synthetase 2 mitochondrial; Alanyl tRNA synthetase like; AlaRS; KIAA1270; MGC69820; Probable alanyl tRNA synthetase mitochondrial; RP11-444E17.1.
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  細胞凋亡  激酶和磷酸酶  線粒體  
分 子 量 115kDa
細胞定位 細胞漿 線粒體

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-AARS2抗體,丙氨酰tRNA合成酶2抗體產(chǎn)品介紹 

      The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011].

Function:
The human alanyl-tRNA synthetase (AlaRS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AlaRS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. Alanyl-tRNA synthetase (AlaRS) catalyzes the ligation of alanine with alanyl-tRNA using ATP.

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