Anti-APCDD1抗體,腺瘤息肉調(diào)節(jié)蛋白抗體產(chǎn)品詳細資料

產(chǎn)品編號 BYK-1565R

英文名稱 APCDD1
中文名稱 腺瘤息肉調(diào)節(jié)蛋白抗體
別    名 adenomatosio polyposis coli down-regulated 1; Adenomatosis polyposis coli down regulated 1; Adenomatosis polyposis coli down regulated 1 protein; APCDD 1; B7323; DRAPC1; FP7019; Protein APCDD1; APCD1_HUMAN.
研究領域 腫瘤  免疫學  生長因子和激素  
分 子 量 56kDa

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應用不做依據(jù)，具體產(chǎn)品應用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-APCDD1抗體,腺瘤息肉調(diào)節(jié)蛋白抗體產(chǎn)品介紹 

      APCDD1 is a novel protein that has been shown to be a target of Wnt/beta catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1 mutated Wilms tumors. [FUNCTION] Probably plays a role in colorectal tumorigenesis. May be a developmental target gene of the Wnt/Beta-catenin pathway.
[SUBCELLULAR LOCATION] Membrane; Single-pass type I membrane protein (Potential). 
[TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderay expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. 
[INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex.

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