Anti-APNG/MPG抗體，N-甲基嘌呤DNA糖基化酶產(chǎn)品詳細(xì)資料

產(chǎn)品編號 BYK-2412R

英文名稱 APNG/MPG
中文名稱 N-甲基嘌呤DNA糖基化酶
別    名 MPG; N-methylpurine-DNA glycosylase isoform a; DNA 3 methyladenine glycosylase; 3 alkyladenine DNA glycosylase; AAG; ADPG; Alkyladenine DNA glycosylase; anpg ; APNG; MDG; N methylpurine DNA glycosirase; CRA36.1; MDG; Mid1; PIG11; PIG16; 3MG_HUMAN.
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號  表觀遺傳學(xué)  
分 子 量 33kDa
細(xì)胞定位 細(xì)胞核 

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-APNG/MPG抗體，N-甲基嘌呤DNA糖基化酶產(chǎn)品介紹 

      MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.

Function:
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

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