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當(dāng)前位置:上海博研生物工程研究中心>>科研抗體>>一抗>> Anti-ACVR2A/ARIP2a抗體,激活素受體2A抗體

Anti-ACVR2A/ARIP2a抗體,激活素受體2A抗體

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     Anti-ACVR2A/ARIP2a抗體,激活素受體2A抗體產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-0804R

英文名稱(chēng) ACVR2A
中文名稱(chēng) 激活素受體2A抗體
別    名 Activin receptor 2A; Activin receptor type 2A; ACTR 2; ACTR IIA; ACTR2; ActRIIa; Acvr 2; Acvr 2A; Acvr2; Acvr2a; OTTHUMP00000197918; ACVR2A; Activin receptor type-2A. 
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  
分 子 量 57kDa

抗體來(lái)源 Mouse or Rabbit
克隆類(lèi)型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù),具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)!

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-ACVR2A/ARIP2a抗體,激活素受體2A抗體產(chǎn)品介紹 


      Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. Activin has been suggested to be an autocrine/paracrine regulator in the human placenta. The presence of ACVR2 mRNA has been deomnstrated in human trophoblast cells and there is also evidence of expression of the gene in human brain and ovary. 

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