Anti-HES4抗體,轉(zhuǎn)錄因子HES4抗體供應(yīng)商產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-11567R

英文名稱 HES4
中文名稱 轉(zhuǎn)錄因子HES4抗體
別    名 bHLH factor Hes4; Hairy and enhancer of split 4; Transcription factor HES 4; HES4_HUMAN.
研究領(lǐng)域 神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
分 子 量 24kDa
細(xì)胞定位 細(xì)胞核 

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-HES4抗體,轉(zhuǎn)錄因子HES4抗體供應(yīng)商產(chǎn)品介紹 

      The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The mammalian homologues of Drosophila hairy and Enhancer of split are the HES gene family members, HES1-6, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. The HES/TLE complex functions by directly binding to DNA, instead of interfering with activator proteins. Most HES family members, including HES1 and HES5, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG). HES2 binds to both N and E box sites, while HES6 does not bind DNA. Rather, HES6 inhibits HES1 activity, thereby promoting transcription. HES1 and HES2 are expressed in a variety of adult and embryonic tissues. HES3 is expressed exclusively in cerebellar Purkinje cells, and HES5 is found solely in the nervous system. HES6 is produced in brain as well as in the limb buds of developing embryos.

 此相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記 

     相關(guān)產(chǎn)品：

     Anti-GBGT1抗體,紅細(xì)胞糖苷α1抗體

Anti-GBP1抗體,G蛋白結(jié)合蛋白1抗體
Anti-GBP6抗體,G蛋白結(jié)合蛋白6抗體
Anti-GCAP1抗體,鳥苷酸環(huán)化酶激活蛋白1抗體
Anti-GCAP3抗體,鳥苷酸環(huán)化酶激活蛋白3抗體
Anti-GCAT抗體,氨基丙酮合成酶抗體
Anti-GCC1抗體,高爾基體卷曲螺旋蛋白1抗體
Anti-GCDH抗體,戊二酰*脫氫酶抗體
Anti-GCHFR抗體,GTP環(huán)反饋調(diào)節(jié)蛋白抗體
Anti-GCM2抗體,絨毛膜特異性轉(zhuǎn)錄因子GCM2抗體
Anti-Gcn1l1抗體,廣泛控制氨基酸合成1樣蛋白1抗體
Anti-GCNT2抗體,β1-6 N-乙酰氨基葡萄糖轉(zhuǎn)移酶2抗體
Anti-GCNT6抗體,β1-6 N-乙酰氨基葡萄糖轉(zhuǎn)移酶6抗體
Anti-GCP4抗體,γ-微管蛋白GCP4抗體
Anti-GCP6抗體,γ-微管蛋白GCP6抗體
Anti-GCS1抗體,β-葡萄糖苷酶1抗體
Anti-GCSH抗體,*裂解系統(tǒng)H蛋白抗體
Anti-GDI1抗體,精神發(fā)育遲滯相關(guān)蛋白R(shí)ab GDI α抗體
Anti-GDPD1抗體,甘油磷酸二酯酶磷酸結(jié)構(gòu)域4抗體
Anti-GDPGP1抗體,15號(hào)染色體開放閱讀框58抗體