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Anti-PD-1/CD279抗體,程序性死亡1抗體產(chǎn)品介紹

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     Anti-PD-1/CD279抗體,程序性死亡1抗體產(chǎn)品介紹產(chǎn)品詳細(xì)資料

產(chǎn)品編號 BYK-1867R

英文名稱 PD-1
中文名稱 程序性死亡1抗體
別    名 programmed death 1; CD279; CD 279; CD279 antigen; hPD 1; PD 1; PD-1; PD1; PDCD 1; PDCD1; Programmed cell death 1; Programmed Cell Death Protein 1; Protein PD 1; SLEB2.
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  
分 子 量 32kDa
細(xì)胞定位 細(xì)胞膜  

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù),具體產(chǎn)品應(yīng)用與實驗稀釋比請!

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-PD-1/CD279抗體,程序性死亡1抗體產(chǎn)品介紹產(chǎn)品介紹 


      This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. 
CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily.

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