Anti-HPV31 E7抗體,人類乳頭狀瘤病毒31 E7抗體說明書產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-10203R

英文名稱 HPV31 E7
中文名稱 人類乳頭狀瘤病毒31 E7抗體
別    名 VE7_HPV31; Protein E7; E7; Human Papilloma Virus; Human papillomavirus type 31 E7; Human papillomavirus type 31 (E7); Human papillomavirus type 31 E7; Human papillomavirus type 31 E7 protein; Protein E7; HPV31 E7 protein.
研究領(lǐng)域 腫瘤  免疫學(xué)  細(xì)菌及病毒  
分 子 量 11kDa

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-HPV31 E7抗體,人類乳頭狀瘤病毒31 E7抗體說明書產(chǎn)品介紹 

      Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximay 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa. Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae. However, some subtypes, notably types 16 and 18, 31 and 33, have been confirmed as agents which cause cervical cancer.

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