【背景資料】:BMP2 (bone morphogenetic protein 2)encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of BMP2 causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. 蛋白別名為:BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A;基因ID為:650;蛋白質(zhì)ID:P12643
【應(yīng)用類型】:WB,IHC-p,ELISA 補(bǔ)充:*的抗體稀釋比例需要基于客戶實(shí)驗(yàn)進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.