Anti-PTEN抗體哪里有賣(mài)

FROM: ABCAM

Catalog Number : BYK-0748R       
Quantity size :   100ug  (0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide)

Anti-PTEN抗體哪里有賣(mài)Background: Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism.

Specificity :   

• Anti-PTEN is a rabbit polyclonal antibody unconjugated                
• specific for PTEN of Human, Mouse, Rat          
• use for western blotting,elisa,immunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification, purity :>95%
• Isotype:  IgG
• molwt:  44kDa

Anti-PTEN抗體哪里有賣(mài)Application :  

• Western blotting 1:100-500                 
• Immunohistochemistry 1:100-500                 
• ELISA 1:500-1000
• IP=1:20-100 
• IF=1:100-500                  
• Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Anti-PTEN抗體哪里有賣(mài)Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.